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[Jun-10] Gut microbiome as a step forward towards personalized medicine

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Speaker:

Prof. Cheng-Yuan Kao

Associate Investigator, National Health Research Institutes

Topic:

Gut microbiome as a step forward towards personalized medicine

Date:

13:30-15:00 Wednesday 10-Jun-2020

Locate

Delta 105

QR code:

qrcode

Link:

https://teams.microsoft.com/l/meetup-join/19%3ac66957ce42ce48d1845c9dd63c464b57%40thread.tacv2/1586261565565?context=%7b%22Tid%22%3a%226c3bc511-43c7-4596-baeb-2335c69c41f1%22%2c%22Oid%22%3a%223cb25719-499f-4b52-ba8d-31e6b47c6cab%22%7d

Hosted by:

Prof. Cheng-Hsin Hsu

Abstract

Microbiota is a collective term for the microorganisms that live in certain habitats including human body and an emerging view is that gut microbiota plays significant roles in regulating host physiology and it could serve as a surrogate means of assessing individual’s disease and health outcomes. Here we report that a dual-specificity phosphatase 6 (Dusp6)-deficient mouse strain harbors dysbiosis–resistant gut/fecal microbiota. We further show that Dusp6-deficiency is a novel host genetic factor that could modulate gut barrier integrity and our multi-omic study provides some hints on how this host-gut-microbiome relationship could be potentially used as complex yet novel biomarkers in selecting fecal microbiota transplantation donors or stratifying patients into responders and non-responders before health-care interventions. In summary, microbiome is the new frontier of personalized medicine treat and prevent diseases with maximized benefit and minimized damage to the individual level.

Bio:

Education History

    1990-1994 B.S. in Biology, National Cheng-Kung University, Tainan, Taiwan.

    1994-1996 M.S. in Genetics, National Yang-Ming University, Taipei, Taiwan.

    2000-2005 Ph.D. in Genetics, University of California – Davis, Davis, CA, USA.

 

Professional Position

    1998-2000 Research Assistant, Institute of Biomedical Sciences, Academia    

              Sinica, Taipei, Taiwan.

    2005-2010 Postdoctoral Researcher, Section of Cell and Developmental Biology,

              University of California – San Diego, La Jolla, CA, USA.

    2010-2011 Postdoctoral Researcher, Department of Internal Medicine, University

              of California – Davis, Davis, CA, USA.

    2011-2012 Assistant Project Scientist, Department of Internal Medicine, 

              University of California – Davis, Davis, CA, USA.

    2012-2017 Assistant Investigator, Immunology Research Center, National Health

              Research Institutes, Zhunan, Miaoli, Taiwan.

    2017-present Associate Investigator, Immunology Research Center, National

                Health Research Institutes, Zhunan, Miaoli, Taiwan.

All faculties and students are welcome to join.

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